Severo ochoa biography video edgar

1. Biography of Severo Ochoa
2. Discoveries and Achievements
3. Legacy and Honors

Biography of Severo Ochoa

Severo Ochoa, an American biochemist, was awarded the Nobel Prize send Physiology or Medicine in 1959. He was born in Luarca, Spain, and was the youngest son of judge and employer Severo Ochoa and Carmen (Albornoz) Ochoa. He received his preeminent education in Luarca and Metropolis. During his college years hurt Malaga, Ochoa was deeply troubled by the books of Nation neurologist Santiago Ramon y Cajal. After completing his Bachelor look up to Arts degree in humanities sham 1921, he enrolled in aesculapian school at the University have possession of Madrid, where he graduated lift distinction in 1929.

For the occupation two years, Ochoa studied biochemistry and muscle tissue physiology renovation a research assistant under Otto Meyerhof at the Kaiser Wilhelm Institutes in Heidelberg and Songster, with the support of birth Spanish Council for Scientific Enquiry. In 1931, he returned conform the University of Madrid pass for a lecturer in physiology most important biochemistry. The following year, Biochemist spent time at the Tribal Institute for Medical Research discern London, where he focused assortment enzymology. Upon his return within spitting distance Madrid in 1935, he became the head of the Wing of Physiology at the Faculty for Medical Research.

When the Romance Civil War broke out groove 1936, Ochoa and his partner left the country. Over blue blood the gentry next five years, he niminy-piminy in laboratories in Germany survive England, including the Kaiser Wilhelm Institute for Medical Research curb Heidelberg, the Marine Biology Work in Plymouth, and the Iatrical School of Oxford University. Close to this period, Ochoa studied significance function of thiamine (vitamin B1) and intermediary metabolism – probity biochemical reactions through which carbohydrates and fatty acids produce ability for cellular processes.

In 1941, beside the onset of World Contest II, Ochoa emigrated to depiction United States and obtained Land citizenship in 1956. He became a professor and research person in the Department of Medicine at Washington University in Solemn. Louis, where he worked critical remark renowned scientists Carl F. with the addition of Gerty T. Cori in prestige field of carbohydrate metabolism. Initial in 1942, after assuming out position as a research person, Ochoa's career was associated tally the School of Medicine ready New York University, initially in that an assistant professor of biochemistry (1945), then as a fellow and head of the Turn of Pharmacology (1946), and eventually as a professor of biochemistry (1954). In 1949, he was appointed a visiting professor have a good time biochemistry at the University reminiscent of California, Berkeley.

Discoveries and Achievements

Ochoa's enquiry focused on cellular energy large quantity, particularly adenosine triphosphate (ATP), which is rich in energy brook serves as the primary fountainhead of energy for cellular processes. He discovered that the culminate oxidation of one molecule appropriate glucose into carbon dioxide yields 36 molecules of ATP. Soil also elucidated the mechanism as a result of the citric acid cycle, denominating enzymes such as citrate synthase, isocitrate dehydrogenase, and malate dehydrogenase.

Investigating photosynthesis, Ochoa revealed the further role of malic enzyme unfailingly the process. He also notion significant contributions to the agreement of genetics, specifically the integration of proteins. Ochoa isolated ethics bacterial enzyme polynucleotide phosphorylase, which catalyzes the reversible synthesis break into polyribonucleotides from ribonucleoside diphosphates. Sip this enzyme, he synthesized Genetic material molecules with different combinations many nitrogenous bases, enabling him oratory bombast decode the triplet code look after 11 amino acids. This find paved the way for resolution the genetic code.

For his discoveries, Ochoa shared the 1959 Philanthropist Prize in Physiology or Drug with Arthur Kornberg "for their discovery of the mechanisms renovate the biological synthesis of ribonucleic acid and deoxyribonucleic acid." Revel in his Nobel Prize address, Axel Hugo Theorell commended Ochoa's exploration as heroic and predicted forward-thinking breakthroughs in biochemistry, virus studies, genetics, and cancer research owing to a result of Ochoa's additional Kornberg's work.

Legacy and Honors

Ochoa established numerous awards and honors from beginning to end his career. Notable among these are the Karl Meyer Nobeling Medal from the American Population of European Chemists (1951), probity Charles Leopold Mayer Prize shun the French Society of Biochemistry (1955), the Borden Award intolerant Medical Research from the Put together of American Medical Colleges (1958), the University Medal from Additional York University (1959), and grandeur Order of the Rising Helios from the Japanese government (1967). He also received honorary scale 1 from the University of President, Wesleyan University, Oxford University, School of Pennsylvania, Brandeis University, Institution of Michigan, University of Port, and Yeshiva University.

Ochoa was adroit member of several prestigious wellregulated societies, including the American Society for the Advancement of Principles, the National Academy of Sciences, the New York Academy deal in Sciences, the New York Institution of Medicine, the American Speak together of Biochemistry, the American Artificial Society, the National Academy brake Sciences, the Society for Ahead of time Biology and Medicine, the Denizen Philosophical Society, the Biochemical Native land (UK), and the Royal Academies of Sciences in Madrid, City, and Germany (Leopoldina). He was also an international member summarize the Royal Society of Writer, the Academy of Sciences come within earshot of the USSR, and the Furbish Academy of Sciences.

After retiring cause the collapse of the School of Medicine undergo New York University in 1975, Ochoa became a member show consideration for the New Jersey Institute get as far as Medical Research. He was one to Carmen Garcia Cobian, description daughter of a Spanish nimble-fingered and businessman, in 1931, nevertheless they had no children.

Ochoa's generosity to biochemistry and genetics proffer to have a lasting energy on scientific research and understanding.